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The U.S. Food and Drug Administration has approved Contrave (naltrexone hydrochloride and bupropion hydrochloride extended-release tablets) as treatment choice for chronic weight-loss in addition to a reduced-calorie diet and physical activity.
Using two separate drugs to shed weight can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight loss and the individuals who go through it you ought to err assisting caution and allow FDA do its job and demand some research be done so your public recognizes the side effects and dangers of the medications before we bring them. Keep in mind that drug companies have been in business to make money and that they would say everything to keep people on the medications.
Researchers found out that participants taking this drug for the year, lost weight within one month and have kept the extra weight off through the 56 weeks from the study. Contrave is often a combination from the drugs naltrexone and bupropion, which appears to reflect a new trend of weight-loss drugs which can be made up of multiple active ingredient, which can make them more effective and safer.
Combo-pilling is the newest fad or also the newest in the future under scrutiny and for that reason it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that by using a combination of pills has become popular is the fact that at the time of right now there are no long term prescription slimming capsules that have been approved by the FDA aside from orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.
Seizures can be a side effect with Contrave and mustn’t be taken in people who have seizure disorders. The drug can also raise blood pressure and heartrate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug.
The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high hypertension, and also by you aren’t heart-related and cerebrovascular (circulation dysfunction impacting your brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical researchers and patients to the increased risk of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.
“There were no signs and symptoms of depression or suicidal thoughts in trial participants,” said Fujioka.