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  • It was found that naltrexone and bupropion combined, that could be marketed in the foreseeable future as Contrave, provide better weight loss results than diet and exercise alone.

    Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the those who go through it you ought to err assisting caution and permit the FDA do its job and demand some investigation be done so that the public is aware of the side effects and hazards of the medications before we drive them. Keep in mind that drug companies are in business to make money and that they would say everything to keep people on his or her medications.

    Researchers found that participants taking this drug to get a year, lost weight within four weeks and have kept the load off through the entire 56 weeks in the study. Contrave is often a combination with the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of more than one active ingredient, which may make them more efficient and safer.

    Combo-pilling is the newest fad or better yet the newest into the future under scrutiny and therefore it is just more publicly known in recent months, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular is the fact that at the time of right now there aren’t long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications however some of the combinations are already rejected or have yet to be licensed by the FDA.

    Seizures really are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug also can raise blood pressure levels and pulse rate, and really should not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with all the drug.

    The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not be used in patients with uncontrolled high blood pressure levels, in addition to by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients on the increased chance of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.

    “There were no signs of depression or suicidal thoughts in trial participants,” said Fujioka.