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  • On September 26, UCLA researcher reported the outcomes of a study, which indicated that Asians who are struggling with alcoholism may benefit especially from naltrexone, among three medications authorized by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a particular mutation which makes them prone to benefit from naltrexone, compared with about 20% of Caucasians and less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director from the UCLA Addictions Laboratory. The findings are available online ( in the journal Neuropsychopharmacology and will also be published in the upcoming print edition with the journal.

    Using two separate drugs to lose weight naturally can be very effective you’ll find combinations while watching FDA now awaiting approval. When dealing with weight-loss and the those who go through it you need to err on the side of caution and allow FDA do its job and demand some research be done so your public knows the side effects and risks of the medications before we take them. Keep in mind that drug companies come in business to make money and that they would say anything to keep people on his or her medications.

    Researchers discovered that participants using this drug for any year, lost weight within one month and have kept the extra weight off through the entire 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which generally seems to reflect a whole new trend of weight-loss drugs which are made up of several active ingredient, that might make them more efficient and safer.

    Combo-pilling is the newest fad or also the newest into the future under scrutiny and therefore it is just more publicly known lately, comb-pilling for weight reduction has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular will be the fact that since right now there aren’t long term prescription diet pills that have been approved by the FDA aside from orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications however some of the combinations have been rejected or have yet to be licensed by the FDA.

    Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise blood pressure levels and heart rate, and must not be used in those with a history of cardiac event or stroke in the last six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy while using drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must not used in patients with uncontrolled high blood pressure, as well as by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting the brain) disease. Patients having a history of cardiac arrest or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert medical professionals and patients towards the increased risk of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for stop smoking.

    The most common effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.