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  • New research released with the Society for the Study of Addiction produced positive news about two prescribed drugs used to help prevent lapse in alcoholics in treatment wanting to stay sober. The drugs, acamprosate (marketing name: Campral) and naltrexone (ReVia) were found to help those struggling in various phases of recovery. Acamprosate helped manage emotional triggers in individuals who had already stopped drinking, naltrexone helped manage cravings in heavy drinkers who are attempting to stop drinking or recently quit.

    Using two separate drugs to lose weight naturally can be very effective you’ll find combinations as you’re watching FDA now awaiting approval. When dealing with weight loss and the people who go through it you ought to err along the side of caution and allow the FDA do its job and demand some research be done in order that the public knows the side effects and perils associated with the medications before we take them. Keep in mind that drug companies have been in business to generate income and that they would say anything to keep people on their medications.

    Researchers found out that participants investing in this drug to get a year, dropped a few pounds within four weeks and have kept the extra weight off through the 56 weeks of the study. Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a new trend of weight-loss drugs that are made up of several active ingredient, which may make them more effective and safer.

    Combo-pilling may be the newest fad or better yet the newest ahead under scrutiny and so it is just more publicly known in recent months, comb-pilling for weight reduction has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular will be the fact that as of right now there are no long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures really are a side effect with Contrave and shouldn’t be taken in individuals with seizure disorders. The drug may also raise blood pressure level and heart rate, and shouldn’t be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure and heartbeat and must ‘t be used in patients with uncontrolled high blood pressure level, and also by anyone with heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert health care professionals and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for quitting smoking.

    Suboxone contains two drugs; buprenorphine and naloxone. The naloxone is irrelevant if your addict uses the medication properly, but if your tablet is dissolved in water and injected the naloxone can cause instant withdrawal. When suboxone is utilized correctly, the naloxone is destroyed within the liver shortly after uptake in the intestines and contains no therapeutic effect. Buprenorphine may be the active substance; it can be absorbed under the tongue (and during the entire mouth) but destroyed by the liver if swallowed. There is a formulation of buprenorphine without naloxone called subutex; I used this formulation when the patient has apparent problems from naloxone, including headaches after dosing with suboxone. I also have treated addicts who may have had gastric bypass, the place that the first section of the intestine is bypassed as well as the stomach contents empty into a more distal section of the small intestine. In such cases the naloxone escapes ?first pass metabolism’, the procedure with normal anatomy where the drug is taken up by the duodenum and transferred right to the liver by the portal vein, where it’s quickly and completely destroyed. After gastric bypass naloxone can be adopted by areas of the intestine which are not served through the portal system, causing blood amounts of naloxone sufficient to cause brief, relatively mild withdrawal symptoms.