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  • Evidence is increasing that addiction without exception is related to problems with the brain’s reward center, specially the mesolimbic system. This area of the problem regulates reward responses in getting food and sex, plus in nurturing infants and children. One of the most important neurotransmitters associated with reward responses, both after they malfunction and once they function properly, is dopamine. What makes opiates unique is that it, among other neurotransmitters modulates “the quantity of dopamine released in in reaction to a stimulus”(Bostwick & Bucci, 2008).

    Using two separate drugs to lose weight naturally can be very effective there are combinations before the FDA now awaiting approval. When dealing with fat loss and the people who go through it you should err along the side of caution and allow FDA do its job and demand some study be done so your public understands the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to make money and that they would say anything to keep people on their own medications.

    Researchers found out that participants using this drug to get a year, lost weight within a month and have kept the extra weight off throughout the 56 weeks from the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more efficient and safer.

    Combo-pilling could be the newest fad or even better the newest into the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills has become popular could be the fact that since right now there are no long term prescription weight loss supplements that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be licensed by the FDA.

    Seizures can be a side effect with Contrave and mustn’t be taken in people who have seizure disorders. The drug can also raise hypertension and heart rate, and must not be used in people who have a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure levels and pulse rate and must not used in patients with uncontrolled high blood pressure levels, as well as by a person with heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients using a history of heart attack or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients for the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stopping smoking.

    To keep up with probably the most current articles from Wendi, the Indiana Addiction Recovery Examiner, go through the subscribe link on top of the page for email notification when new articles are published. Please leave a comment for virtually any article.