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  • On September 26, UCLA researcher reported the outcome of a study, which indicated that Asians who are struggling with alcoholism will manage to benefit especially from naltrexone, among three medications approved by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has found out that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent have a very particular mutation that produces them more likely to benefit from naltrexone, in comparison with about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director with the UCLA Addictions Laboratory. The findings are still available online ( inside the journal Neuropsychopharmacology and will be published within an upcoming print edition from the journal.

    Using two separate drugs to lose weight naturally can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the people who go through it you ought to err assisting caution and allow FDA do its job and demand some investigation be done so that the public is aware of the side effects and dangers of the medications before we bring them. Keep in mind that drug companies will be in business to generate income and that they would say everything to keep people on their own medications.

    Researchers found out that participants using this drug to get a year, dropped excess weight within four weeks and have kept the load off through the entire 56 weeks in the study. Contrave can be a combination from the drugs naltrexone and bupropion, which generally seems to reflect a brand new trend of weight-loss drugs which might be made up of multiple active ingredient, which might make them far better and safer.

    Combo-pilling is the newest fad or even better the newest in the future under scrutiny and so it is just more publicly known recently, comb-pilling for weight loss has been around since the eighties. The biggest reason that employing a combination of pills is starting to become popular will be the fact that as of right now there are no long term prescription diet pills that have been authorized by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications even though some of the combinations are actually rejected or have yet to be approved by the FDA.

    Seizures certainly are a side effect with Contrave and really should not be taken in people who have seizure disorders. The drug could also raise blood pressure level and heart rate, and really should not be used in people who have a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartrate and must stop used in patients with uncontrolled high blood pressure levels, and also by a person with heart-related and cerebrovascular (circulation system dysfunction impacting the mind) disease. Patients with a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes having a boxed warning to alert medical professionals and patients towards the increased probability of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.

    “There were no warning signs of depression or suicidal thoughts in trial participants,” said Fujioka.